This target displays homology in the following species: Cow: 93%; Human: 93%; Mouse: 100%; Pig: 93%; Rat: 100%
RGS10 inhibits signal transduction by increasing the GTPASE activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. It associates specifically with the activated forms of the G protein subunits G(I)-ALPHA and G(Z)- alpha but fails to interact with the structurally and functionally distinct G(S)-alpha subunit. Activity on G(Z)-alpha is inhibited by palmitoylation of the G-protein.
蛋白别名: Regulator of G-protein signaling 10; RGS10
基因别名: 2310010N19Rik; Rgs10
UniProt ID: (Mouse) Q9CQE5
Entrez Gene ID: (Mouse) 67865