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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:250-1:1,000 | - |
免疫细胞化学 (ICC/IF) |
1:100 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Synthetic peptide (aa 119-137 , CEDFKKSKGPQQIHLKAKA) of RGS18 protein. |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
Conc. Not Determined |
保存液 |
whole serum with 50% glycerol |
内含物 |
0.025% sodium azide |
保存条件 |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2540639 |
This gene encodes a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Regulator of G-protein signaling 18; regulator of G-protein signalling 13; regulator of G-protein signalling 18; RGS18; RP11-142L4.1
基因别名: RGS13; RGS18
UniProt ID: (Human) Q9NS28
Entrez Gene ID: (Human) 64407
分子生物学功能:
GTPase-activating protein
