RGS19 inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, predominantly to G(i)-alpha-3. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein.
蛋白别名: G alpha interacting protein; G protein signalling regulator 19; G-alpha interacting protein; G-alpha-interacting protein; GAIP; GAIP protein; GS19; guanine nucleotide binding protein alpha inhibiting activity polypeptide 3 interacting protein; Regulator of G-protein signaling 19; regulator of G-protein signalling 19; RGS19
基因别名: 2610042F04Rik; AI324841; AW547781; GAIP; GNAI3IP; RGS19; RGSGAIP
分子生物学功能: GTPase-activating protein