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Invitrogen
RGS3 Polyclonal Antibody
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产品信息
PA5-79925
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence at the C-terminus of mouse RGS3 (909-925aa DSYTREHTKENLQSITR).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide, 0.05mg thimerosal
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: Rat Testis Tissue, Rat Brain Tissue, Rat Spleen Tissue, HELA Cell, U87 Cell. IHC: Rat Intestine Tissue.
靶标信息
This gene encodes a member of the regulator of G-protein signaling (RGS) family. This protein is a GTP-ase activating protein which inhibits G-protein mediated signal transduction. The protein is largely cytosolic, but G-protein activation leads to translocation of this protein to the plasma membrane. A nuclear form of this protein has also been described, but its sequence has not been identified. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature of some transcripts is not yet known.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C2 membrane binding, PDZ protein/protein interaction, ATP/GTP binding domains; C2PA; FLJ20370; FLJ31516; FLJ90496; Regulator of G-protein signaling 3; regulator of G-protein signalling 3; RGP3; RGS3; SRB-RGS
基因别名: 4930506N09Rik; C2PA; C2PA-RGS3; PDZ-RGS3; RGP3; RGS3; RGS3S; SRB-RGS
UniProt ID: (Human) P49796, (Mouse) Q9DC04, (Rat) P49797
Entrez Gene ID: (Human) 5998, (Mouse) 50780, (Rat) 54293
inactivation of MAPK activity
regulation of G-protein coupled receptor protein signaling pathway
positive regulation of GTPase activity
signal transduction
G-protein coupled receptor signaling pathway
negative regulation of signal transduction
termination of G-protein coupled receptor signaling pathway
