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Proteintech
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This antibody got about 58kD in the mouse eye and 70kD in the mouse brain in western blotting, both in line with their expected masses. Defects in RGS9 are a cause of prolonged electroretinal response suppression (PERRS).
Immunogen sequence: SGENLGFWE ACEDLKYGDQ SKVKEKAEEI YKLFLAPGAR RWINIDGKTM DITVKGLKHP HRYVLDAAQT HIYMLMKKDS YARYLKSPIY KDMLAKAIEP QETTKKSSTL PFMRRHLRSS PSPVILRQLE EEAKAREAAN TVDITQPGQH MAPSPHLTVY TGTCMPPSPS SPFSSSCRSP RKPFASPSRF IRRPSTTICP SPIRVALESS SGLEQKGECS GSMAPRGPSV TESSEASLDT SWPRSRPRAP PKARMALSFS RFLRRGCLAS PVFARLSPKC PAVSHGRVQP LGDVGQQLPR LKSKRVANFF QIKMDVPTGS GTCLMDSEDA GTGESGDRAT EKEVICPWES L (273-622 aa encoded by BC022504)
The cascade of biochemical reactions within the vision system is complex and contains numerous steps taking place in nanoseconds. RGS is a family of GTPase accelerating proteins (GAPs). RGS9 is a member of this family and is the predominant source of GAP activity in rod outer segments. RGS9-1, found predominately in vertebrate cone and rod photoreceptors, is a useful model for understanding how rapid recovery kinetics of the light responses in retinal photoreceptors take place.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MGC111763; MGC26458; Regulator of G-protein signaling 9; regulator of G-protein signalling 9; RGS9; ROS GAP
基因别名: PERRS; RGS9; RGS9-1; Rgs9-2; RGS9L
UniProt ID: (Human) O75916, (Rat) P49805, (Mouse) O54828
Entrez Gene ID: (Human) 8787, (Rat) 29481, (Mouse) 19739