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Proteintech
RILPL1 Polyclonal Antibody
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产品信息
16732-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
RILPL1 Fusion Protein Ag10192 (1-252 aa encoded by BC080626)
偶联物
形式
Liquid
浓度
0.31 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MTGMSERER QVMKKLKEVV DKQRDEIRAK DRELGLKNED VEALQQQQTR LMKINHDLRH RVTVVEAQGK ALIEQKVELE ADLQTKEQEM GSLRAELGKL RERLQGEHSQ NGEEEPETEP VGEESISDAE KVAMDLKDPN RPRFTLQELR DVLHERNELK SKVFLLQEEL AYYKSEEMEE ENRIPQPPPI AHPRTSPQPE SGIKRLFSFF SRDKKRLANT QRNVHIQESF GQWANTHRDD GYTEQGQEAL QHL (1-252 aa encoded by BC080626)
靶标信息
Plays a role in the regulation of cell shape and polarity. Plays a role in cellular protein transport, including protein transport away from primary cilia. Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus. Competes with SIAH1 for binding GAPDH. Does not regulate lysosomal morphology and distribution (PubMed:14668488). Binds to RAB10 following LRRK2-mediated RAB10 phosphorylation which leads to inhibition of ciliogenesis (PubMed:30398148). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: GAPDH competitor of SIAH protein enhances life; GAPDH's competitor of SIAH1 protein enhances life; GOSPEL; Rab interacting lysosomal protein-like 1; Rab-interacting lysosomal-like protein 1; RILP-like protein 1
基因别名: 2900002H16Rik; 6330559I19Rik; GOSPEL; MNCb-2440; RGD1307973; RILPL1; RLP1
UniProt ID: (Human) Q5EBL4, (Mouse) Q9JJC6, (Rat) D3ZUQ0
Entrez Gene ID: (Human) 353116, (Mouse) 75695, (Rat) 304469
