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Abnova
RILPL1 Polyclonal Antibody, MaxPab™
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产品信息
H00353116-B01P
产品规格
种属反应
Human,
Rat
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
RILPL1 (NP_847884.1, 1 a.a. approximately 362 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5-1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MDVYDIASLV GHEFERVIDQ HGCEAIARLM PKVVRVLEIL EVLVSRHHVA PELDELRLEL DRLRLERMDR IEKERKHQKE LELVEDVWRG EAQDLLSQIA QLQEENKQLM TNLSHKDVNF SEEEFQKHEG MSERERQVMK KLKEVVDKQR DEIRAKDREL GLKNEDVEAL QQQQTRLMKI NHDLRHRVTV VEAQGKALIE QKVELEADLQ TKEQEMGSLR AELGKLRERL QGEHSQNGEE EPETEPVGEE SISDAEKVAM DLKDPNRPRF TLQELRDVLH ERNELKSKVF LLQEELAYYK SEEMEEENRI PQPPPIAHPR TSPQPESGIK RLIFTAIMPM VAAGLIIDDP TLQPVRRLVS LV
靶标信息
Plays a role in the regulation of cell shape and polarity. Plays a role in cellular protein transport, including protein transport away from primary cilia. Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus. Competes with SIAH1 for binding GAPDH. Does not regulate lysosomal morphology and distribution (PubMed:14668488). Binds to RAB10 following LRRK2-mediated RAB10 phosphorylation which leads to inhibition of ciliogenesis (PubMed:30398148). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GAPDH competitor of SIAH protein enhances life; GAPDH's competitor of SIAH1 protein enhances life; GOSPEL; Rab interacting lysosomal protein-like 1; Rab-interacting lysosomal-like protein 1; RILP-like protein 1
基因别名: GOSPEL; RGD1307973; RILPL1; RLP1
UniProt ID: (Human) Q5EBL4, (Rat) D3ZUQ0
Entrez Gene ID: (Human) 353116, (Rat) 304469
