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Invitrogen
RIMBP2 Polyclonal Antibody
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产品信息
PA5-60614
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: RVDNITQISA QLSWLPTNSN YSHVIFLNEE EFDIVKAARY KYQFFNLRPN MAYKVKVLAK PHQMPWQLPL EQREKKEAFV EFSTLP
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.
靶标信息
The presynaptic active zone mediates synaptic vesicle exocytosis at a synapse. RIM proteins are active zone scaffolding molecules that--among others--mediate vesicle priming and directly or indirectly interact with most other essential presynaptic proteins. RIMBP2 encodes RIMS-binding protein 2 belonging to RIMBP family. RIMBP2 is supposed to be localized at cell membrane especially synaptic plasma membrane. By interacting with RIMS1, RIMS2, CACNA1D and CACNA1B via the SH3 domains, RIMBP2 mediates synaptic transmission as bifunctional linker.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: protein phosphatase 1, regulatory subunit 133; RIM binding protein 2; RIM-BP2; RIMS-binding protein 2
基因别名: KIAA0318; PPP1R133; RBP2; RIM-BP2; RIMBP2
UniProt ID: (Human) O15034
Entrez Gene ID: (Human) 23504
