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Immunogen sequence: HKCILKPLKG HVEAMLKDFH MADGSWKQLK ENLQLVRQRN PQELGVFAPT PDFVDVEKIK VKFMTMQKMY SPEKKVMLLL RVCKLIYTVM ENNSGRMYGA DDFLPVLTYV IAQCDMLELD TEIEYMMELL DPSLLHGEGG YYLTSAYGAL SLIKNFQEEQ AARLLSSETR DTLRQWHKRR TTNRTIPSVD DFQNYLRVAF QEVNSGCTGK TLLVRPYITT EDVCQICAEK FKVGDPEEYS LFLFVDETWQ QLAEDTYPQK IKAELHSRPQ PHIFHFVYKR IKNDPYGIIF QNGEEDLTTS
The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: RAB5 interacting protein 2; Ras and Rab interactor 2; RAS association (RalGDS/AF-6) domain containing protein JC265; RAS association domain family 4; RAS inhibitor JC265; RAS interaction/interference protein 2
基因别名: 2010003K16Rik; 4632403N06Rik; AW821980; MACS; RASSF4; RIN2
UniProt ID: (Human) Q8WYP3, (Mouse) Q9D684
Entrez Gene ID: (Human) 54453, (Mouse) 74030