Invitrogen

RNF14 Polyclonal Antibody

产品信息

PA5-50873

应用	建议稀释比	已发表文章
免疫印迹 (WB)	1:200-1:1,000	-
免疫组化（石蜡） (IHC (P))	1:25-1:100	-

产品规格
种属反应	Human, Mouse
宿主/亚型	Rabbit / IgG
分类	Polyclonal
类型	Antibody
抗原	Fusion protein corresponding to residues near the N terminal of human ring finger protein 14 查看免疫原
偶联物	Unconjugated
形式	Liquid
浓度	1.2 mg/mL
纯化类型	Antigen affinity chromatography
保存液	PBS, pH 7.4, with 40% glycerol
内含物	0.05% sodium azide
保存条件	-20°C
RRID	AB_2636325

产品详细信息

The antibody detects endogenous levels of total RNF14 protein.

靶标信息

The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: androgen receptor associated protein 54; Androgen receptor-associated protein 54; E3 ubiquitin-protein ligase RNF14; HFB30; Protein Triad2; RING finger protein 14; Triad2 protein; TRIAD2 type I

基因别名: 2310075C09Rik; 2610005D23Rik; AA986456; ARA54; AU041447; D18Ertd188e; D7Bwg0165e; HFB30; HRIHFB2038; RNF14; TRIAD2

UniProt ID: (Human) Q9UBS8, (Mouse) Q9JI90

Entrez Gene ID: (Human) 9604, (Mouse) 56736

分子生物学功能: ubiquitin-protein ligase