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Abnova
RNF14 Monoclonal Antibody (4G9)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00009604-M01
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
4G9
抗原
RNF14 (NP_004281, 217 a.a. approximately 316 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
Immunogen sequence: LFLCSICFCE KLGSECMYFL ECRHVYCKAC LKDYFEIQIR DGQVQCLNCP EPKCPSVATP GQVKELVEAE LFARYDRLLL QSSLDLMADV VYCPRPCCQL
靶标信息
The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: androgen receptor associated protein 54; HFB30; HRIHFB2038; RNF14; unnamed protein product
基因别名: ARA54; HFB30; HRIHFB2038; TRIAD2
UniProt ID: (Human) Q9UBS8
Entrez Gene ID: (Human) 9604
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
ubiquitin-dependent protein catabolic process
signal transduction
protein ubiquitination
androgen receptor signaling pathway
positive regulation of transcription, DNA-templated
regulation of androgen receptor signaling pathway
regulation of canonical Wnt signaling pathway
rescue of stalled ribosome
protein K6-linked ubiquitination
protein-RNA covalent cross-linking repair
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
