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Recommended positive controls: U87-MG.
Predicted reactivity: Mouse (99%), Rat (99%), Xenopus laevis (93%), Chicken (91%), Bovine (94%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
RNF166 (RING finger protein 166) is a 237 amino acid protein that contains one RING-type zinc finger and a UIM (ubiquitin-interacting motif) repeat. Existing as two alternatively spliced isoforms, RNF166 is encoded by a gene that maps to human chromosome 16q24.3. Chromosome 16 encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: E3 ubiquitin-protein ligase RNF166; RING finger protein 166; RING-type E3 ubiquitin transferase RNF166
基因别名: RNF166
UniProt ID: (Human) Q96A37
Entrez Gene ID: (Human) 115992