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Invitrogen
RNF183 Polyclonal Antibody
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产品信息
PA5-23862
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 86-114 amino acids from the central region of human RNF183
偶联物
形式
Liquid
浓度
Lot-specific
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
产品详细信息
This antibody is predicted to react with bovine based on sequence homology.
靶标信息
Acts as a E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins (PubMed:29507230). Triggers apoptosis in response to prolonged ER stress by mediating the polyubiquitination and subsequent proteasomal degradation of BCL2L1 (PubMed:29507230). May collaborate with FATE1 to restrain BIK protein levels thus regulating apoptotic signaling (PubMed:26567849). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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