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Proteintech
RNF40 Polyclonal Antibody
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产品信息
15621-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
RNF40 Fusion Protein Ag8047 (700-1001 aa encoded by BC006133)
偶联物
形式
Liquid
浓度
0.33 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: VDELRSRIR ELEERDRRES KKIADEDALR RIRQAEEQIE HLQRKLGATK QEEEALLSEM DVTGQAFEDM QEQNGRLLQQ LREKDDANFK LMSERIKANQ IHKLLREEKD ELGEQVLGLK SQVDAQLLTV QKLEEKERAL QGSLGGVEKE LTLRSQALEL NKRKAVEAAQ LAEDLKVQLE HVQTRLREIQ PCLAESRAAR EKESFNLKRA QEDISRLRRK LEKQRKVEVY ADADEILQEE IKEYKARLTC PCCNTRKKDA VLTKCFHVFC FECVRGRYEA RQRKCPKCNA AFGAHDFHRI YIS (700-1001 aa encoded by B C006133)
靶标信息
The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 95 kDa retinoblastoma protein binding protein; 95 kDa retinoblastoma-associated protein; BRE1 E3 ubiquitin ligase homolog B; BRE1-B; DKFZp686K191; E3 ubiquitin-protein ligase BRE1B; MGC13051; Protein staring; Rb-associated protein; RBP95; RING finger protein 40; ring finger protein 40, E3 ubiquitin protein ligase; RING-type E3 ubiquitin transferase BRE1B; staring protein; Syntaxin-1-interacting RING finger protein
基因别名: AI848422; BRE1B; KIAA0661; mKIAA0661; RBP95; RNF40; STARING
UniProt ID: (Human) O75150, (Rat) Q8CJB9, (Mouse) Q3U319
Entrez Gene ID: (Human) 9810, (Rat) 266712, (Mouse) 233900
mRNA 3'-UTR binding
ubiquitin-protein transferase activity
protein binding
zinc ion binding
ligase activity
syntaxin-1 binding
ubiquitin conjugating enzyme binding
ubiquitin protein ligase binding
protein complex binding
protein homodimerization activity
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
ubiquitin-dependent protein catabolic process
regulation of mitotic cell cycle
histone monoubiquitination
histone H2B ubiquitination
response to peptide hormone
negative regulation of mRNA polyadenylation
positive regulation of proteasomal protein catabolic process
positive regulation of protein polyubiquitination
positive regulation of histone H2B ubiquitination
chromatin modification
