Invitrogen

RNF7 Polyclonal Antibody

产品信息

PA5-50872

应用	建议稀释比	已发表文章
免疫印迹 (WB)	1:200-1:1,000	-
免疫组化（石蜡） (IHC (P))	1:10-1:50	-

产品规格
种属反应	Human, Mouse
宿主/亚型	Rabbit / IgG
分类	Polyclonal
类型	Antibody
抗原	Full length fusion protein of Human RNF7 查看免疫原
偶联物	Unconjugated
形式	Liquid
浓度	1 mg/mL
纯化类型	Antigen affinity chromatography
保存液	PBS, pH 7.4, with 40% glycerol
内含物	0.05% sodium azide
保存条件	-20°C
RRID	AB_2636324

产品详细信息

The antibody detects endogenous levels of total RNF7 protein.

靶标信息

The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。

引用该产品

生物信息学

蛋白别名: CKBBP1; CKII beta-binding protein 1; OTTHUMP00000180645; Rbx2; Regulator of cullins 2; RING finger protein 7; RING-box protein 2; Sensitive to apoptosis gene protein; sensitive to apoptosis, zinc RING finger protein SAG, regulator of cullins 2; zinc RING finger protein SAG

基因别名: CKBBP1; RBX2; RNF7; ROC2; SAG

UniProt ID: (Human) Q9UBF6, (Mouse) Q9WTZ1

Entrez Gene ID: (Human) 9616, (Mouse) 19823

分子生物学功能: ubiquitin-protein ligase protein modifying enzyme