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Abnova
RNPS1 Monoclonal Antibody (7G8)
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产品信息
H00010921-M05
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
7G8
抗原
RNPS1 (NP_006702, 158 a.a. approximately 239 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.44 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: PKPTKVHIGR LTRNVTKDHI MEIFSTYGKI KMIDMPVERM HPHLSKGYAY VEFENPDEAE KALKHMDGGQ IDGQEITATA VL
靶标信息
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Two splice variants have been found for this gene; both variants encode the same protein.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ribonucleic acid binding protein S1; RNA binding protein S1, serine-rich domain; RNA binding protein with serine-rich domain; RNA-binding protein S1, serine-rich domain; RNA-binding protein with serine-rich domain 1; SR protein; SR-related protein LDC2
基因别名: E5.1; LDC2; RNPS1
UniProt ID: (Human) Q15287, (Rat) Q6AYK1, (Mouse) Q99M28
Entrez Gene ID: (Human) 10921, (Rat) 287113, (Mouse) 19826
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
regulation of alternative mRNA splicing, via spliceosome
mRNA splicing, via spliceosome
transcription, DNA-templated
termination of RNA polymerase II transcription
RNA export from nucleus
mRNA export from nucleus
RNA splicing
mRNA 3'-end processing
positive regulation of apoptotic process
negative regulation of mRNA splicing, via spliceosome
mRNA processing
biological_process
