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In Western Blot, bands at 85 kDa and 107 kDa are observed, representing different isoforms of ROBO4 protein.
Suggested positive control: HUVEC lysate, antigen standard for ROBO4 (transient overexpression lysate).
Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins. Involved in the maintenance of endothelial barrier organization and function (PubMed:30455415). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FLJ20798; Magic roundabout; MGC133352; MGC133353; Roundabout homolog 4; roundabout homolog 4, magic roundabout; roundabout, axon guidance receptor, homolog 4
基因别名: ECSM4; MRB; ROBO4; UNQ421/PRO3674
UniProt ID: (Human) Q8WZ75
Entrez Gene ID: (Human) 54538