Proteintech

RORB Polyclonal Antibody

Name: RORB Polyclonal Antibody
Brand: Proteintech
SKU: 17635-1-AP

2 篇参考文献

查看其他13个RORB抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (13)

RORB Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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RORB Antibody (17635-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded mouse brain tissue slide using 17635-1-AP (RORB antibody) at dilution of 1:200 (under 10x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

RORB Antibody in Immunoprecipitation (IP)

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Immunogen image

Immunogen Image RORB Polyclonal Antibody

产品信息

17635-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

免疫组化（石蜡） (IHC (P))

1:50-1:500

免疫细胞化学 (ICC/IF)

查看2篇已发表文章 2篇已发表文章

免疫沉淀 (IP)

0.5-4.0 µg

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

RORB Fusion Protein Ag11910 (106-459 aa encoded by BC051830)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.25 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: EQRQQQSGE AEALARVYSS SISNGLSNLN NETSGTYANG HVIDLPKSEG YYNVDSGQPS PDQSGLDMTG IKQIKQEPIY DLTSVPNLFT YSSFNNGQLA PGITMTEIDR IAQNIIKSHL ETCQYTMEEL HQLAWQTHTY EEIKAYQSKS REALWQQCAI QITHAIQYVV EFAKRITGFM ELCQNDQILL LKSGCLEVVL VRMCRAFNPL NNTVLFEGKY GGMQMFKALG SDDLVNEAFD FAKNLCSLQL TEEEIALFSS AVLISPDRAW LIEPRKVQKL QEKIYFALQH VIQKNHLDDE TLAKLIAKIP TITAVCNLHG EKLQVFKQSH PEIVNTLFPP LYKELFNPDC ATGCK (106-459 aa encoded by BC051830)

靶标信息

Retinoid-related orphan receptor beta (ROR beta), a NR1 thyroid hormone receptor, affects the development and functioning of the central nervous system, including sensory input integration and circadian timing. Disruption of ROR beta in mice results in juvenile ataxia, retinal degeneration, circadian activity abnormalities, and delayed onset of male fertility. ROR beta binds to the monomeric response elements containing the sequence AnnTAGGTCA as a monomer. An alternatively spliced isoform, ROR beta2, has been isolated from rats, and the expression of ROR beta2 is confined to the pineal gland and retina. ROR beta2 shares common DNA- and putative ligand-binding domains with wild-type ROR beta but is characterized by a different amino-terminal domain. ROR beta expression has been documented in various regions of the mouse brain.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

生物信息学

蛋白别名: Nuclear receptor ROR-beta; Nuclear receptor RZR-beta; Nuclear receptor subfamily 1 group F member 2; RAR-related orphan receptor B; RAR-related orphan receptor beta; retinoic acid-binding receptor beta; retinoid-related orphan receptor beta; Retinoid-related orphan receptor-beta; transcription factor

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基因别名: bA133M9.1; NR1F2; ROR-BETA; Rorb; Rorbeta; RZR-BETA; RZRB

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UniProt ID: (Mouse) Q8R1B8

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Entrez Gene ID: (Human) 6096, (Rat) 309288, (Mouse) 225998

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功能