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Antibody detects endogenous levels of total RPAP1.
RNA polymerases transcribe nuclear genes for ribosomal RNA and are integral components of ribosomal biogenesis. RNA polymerase I (Pol I) is located in the nucleolus and transcribes class I genes, which code for large ribosomal RNA. RNA polymerase II (Pol II) synthesizes mRNA. RNA polymerase III (Pol III) transcribes class III genes, encoding a number of small ribosomal RNA molecules including tRNA and 5S rRNA. RPAP1 (RNA polymerase II associated protein 1) is a 1, 393 amino acid nuclear protein that is thought to connect Pol II to acetylated Histone H3 and regulators of protein complex formation. A member of the RPAP1 family, RPAP1 exists as three alternatively spliced isoforms that are encoded by a gene that maps to human chromosome 15q15.1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: RNA polymerase II-associated protein 1; RPAP-1
基因别名: KIAA1403; RPAP1
UniProt ID: (Human) Q9BWH6
Entrez Gene ID: (Human) 26015