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Invitrogen
RRAGA/RRAGB Polyclonal Antibody
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产品信息
PA5-51994
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human RRAGA/RRAGB
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: FDVEHSHVRF LGNLVLNLWD CGGQDTFMEN YFTSQRDNIF RNVEVLIYVF DVESRELEKD MHYYQSCLEA ILQNSPDAKI FCLVHKMDLV QEDQRDLIFK EREEDLRRLS RPLECSCF
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
靶标信息
Ras-homologous GTPases constitute a large family of signal transducers that alternate between an activated, GTP-binding state and an inactivated, GDP-binding state. These proteins represent cellular switches that are operated by GTP-exchange factors and factors that stimulate their intrinsic GTPase activity. All GTPases of the Ras superfamily have in common the presence of six conserved motifs involved in GTP/GDP binding, three of which are phosphate-/magnesium-binding sites (PM1-PM3) and three of which are guanine nucleotide-binding sites (G1-G3). Transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Adenovirus E3 14.7 kDa-interacting protein 1; adenovirus E3-14.7K interacting protein 1; FIP-1; GTP-binding protein ragB; Rag A; Rag B; Ras-related GTP binding A; Ras-related GTP binding B; Ras-related GTP-binding protein A; Ras-related GTP-binding protein B; RRAGA; RRAGB
基因别名: bA465E19.1; FIP-1; FIP1; RAGA; RAGB; RRAGA; RRAGB
UniProt ID: (Human) Q15347, (Human) Q5VZM2
Entrez Gene ID: (Human) 10670, (Human) 10325
apoptotic process
cell cycle arrest
cell death
negative regulation of autophagy
macroautophagy
modulation by virus of host morphology or physiology
positive regulation of TOR signaling
cellular response to amino acid starvation
cellular protein localization
positive regulation of cytolysis
cellular response to amino acid stimulus
positive regulation of TORC1 signaling
regulation of autophagy
regulation of TOR signaling
