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Proteintech
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Immunogen sequence: MEESDSEKT TEKENLGPRM DPPLGEPEGS LGWVLPNTAM KKKVLLMGKS GSGKTSMRSI IFANYIARDT RRLGATIDVE HSHVRFLGNL VLNLWDCGGQ DTFMENYFTS QRDNIFRNVE VLIYVFDVES RELEKDMHYY QSCLEAILQN SPDAKIFCLV HKMDLVQEDQ RDLIFKEREE DLRRLSRPLE CSCFRTSIWD ETLYKAWSSI VYQLIPNVQQ LEMNLRNFAE IIEADEVLLF ERATFLVISH YQCKEQRDAH RFEKISNIIK QFKLSCSKLA ASFQSMEVRN SNFAAFIDIF TSNTYVMVVM SDPSIPSAAT LINIRNARKH FEKLERVDGP KQCLLMR (1-346 aa encoded by BC034726)
Ras-homologous GTPases constitute a large family of signal transducers that alternate between an activated, GTP-binding state and an inactivated, GDP-binding state. These proteins represent cellular switches that are operated by GTP-exchange factors and factors that stimulate their intrinsic GTPase activity. All GTPases of the Ras superfamily have in common the presence of six conserved motifs involved in GTP/GDP binding, three of which are phosphate-/magnesium-binding sites (PM1-PM3) and three of which are guanine nucleotide-binding sites (G1-G3). Transcript variants encoding distinct isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: GTP-binding protein ragB; Rag B; ragB; Ras-related GTP binding B; Ras-related GTP-binding protein B; RRAGB; rragB {ECO:0000312|RGD:619805}
基因别名: bA465E19.1; RAGB; RRAGB
UniProt ID: (Human) Q5VZM2, (Rat) Q63487, (Mouse) Q6NTA4
Entrez Gene ID: (Human) 10325, (Rat) 117043, (Mouse) 245670