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Abnova
RRAGB Monoclonal Antibody (2B8)
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产品信息
H00010325-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
2B8
抗原
RRAGB (AAH34726, 1 a.a. approximately 346 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.32 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
Immunogen sequence: MEESDSEKTT EKENLGPRMD PPLGEPEGSL GWVLPNTAMK KKVLLMGKSG SGKTSMRSII FANYIARDTR RLGATIDVEH SHVRFLGNLV LNLWDCGGQD TFMENYFTSQ RDNIFRNVEV LIYVFDVESR ELEKDMHYYQ SCLEAILQNS PDAKIFCLVH KMDLVQEDQR DLIFKEREED LRRLSRPLEC SCFRTSIWDE TLYKAWSSIV YQLIPNVQQL EMNLRNFAEI IEADEVLLFE RATFLVISHY QCKEQRDAHR FEKISNIIKQ FKLSCSKLAA SFQSMEVRNS NFAAFIDIFT SNTYVMVVMS DPSIPSAATL INIRNARKHF EKLERVDGPK QCLLMR
靶标信息
Ras-homologous GTPases constitute a large family of signal transducers that alternate between an activated, GTP-binding state and an inactivated, GDP-binding state. These proteins represent cellular switches that are operated by GTP-exchange factors and factors that stimulate their intrinsic GTPase activity. All GTPases of the Ras superfamily have in common the presence of six conserved motifs involved in GTP/GDP binding, three of which are phosphate-/magnesium-binding sites (PM1-PM3) and three of which are guanine nucleotide-binding sites (G1-G3). Transcript variants encoding distinct isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GTP-binding protein ragB; Rag B; Ras-related GTP binding B; Ras-related GTP-binding protein B; RRAGB
基因别名: bA465E19.1; RAGB; RRAGB
UniProt ID: (Human) Q5VZM2
Entrez Gene ID: (Human) 10325
