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Invitrogen
RUVBL1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-89672
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-214 of human RUVBL1/TIP49A/PONTIN (NP_0036981)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.58 mg/mL
规格
158 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MKIEEVKSTT KTQRIASHSH VKGLGLDESG LAKQAASGLV GQENAREACG VIVELIKSKK MAGRAVLLAG PPGTGKTALA LAIAQELGSK VPFCPMVGSE VYSTEIKKTE VLMENFRRAI GLRIKETKEV YEGEVTELTP CETENPMGGY GKTISHVIIG LKTAKGTKQL KLDPSIFESL QKERVEAGDV IYIEANSGAV KRQGRCDTYA TEFD; Positive Samples: MCF-7, HeLa, 293T, Mouse testis, Mouse spleen, Rat testis; Cellular Location: Cytoplasm, Membrane, Nucleus, Nucleus matrix, centrosome, cytoskeleton, microtubule organizing center, nucleoplasm
靶标信息
The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 49 kDa TATA box-binding protein-interacting protein; 49 kDa TBP-interacting protein; DNA helicase p50; Pontin 52; RuvB-like 1; RuvB-like protein 1; TIP49a; TIP60-a
基因别名: 2510009G06Rik; NMP238; Pontin52; Ruvbl1; Tip49; Tip49a
UniProt ID: (Rat) P60123, (Mouse) P60122
Entrez Gene ID: (Rat) 65137, (Mouse) 56505
DNA repair
DNA recombination
transcription, DNA-templated
regulation of transcription, DNA-templated
mitotic nuclear division
positive regulation of plasminogen activation
DNA duplex unwinding
regulation of growth
histone H4 acetylation
histone H2A acetylation
cell division
regulation of fibroblast apoptotic process
cellular response to DNA damage stimulus
cell cycle
chromatin modification
regulation of mitophagy
positive regulation of protein targeting to mitochondrion
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
