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Invitrogen
RXFP2 Polyclonal Antibody
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RXFP2 Antibody (PA5-89738) in WB
Western blot analysis of RXFP2 in extracts of various cell lines. Samples were incubated with RXFP2 Polyclonal antibody (Product # PA5-89738) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
产品信息
PA5-89738
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 80-180 of human RXFP2 (NP_5707181)
偶联物
形式
Liquid
浓度
1.44 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: CGDTSGWATI FGTVHGNANS VALTQECFLK QYPQCCDCKE TELECVNGDL KSVPMISNNV TLLSLKKNKI HSLPDKVFIK YTKLKKIFLQ HNCIRHISRK A; Positive Samples: Mouse kidney, Rat kidney; Cellular Location: Cell membrane, Multi-pass membrane protein
靶标信息
The activity of this relaxin receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP and may also be a receptor for Leydig insulin-like peptide. Expressed in embryonic and adult gonads of males and females, as well in male gubernarculum and in brain. Not detected in kidney, spleen and heart.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: G protein coupled receptor affecting testicular descent; G protein-coupled receptor 106; G-protein coupled receptor 106; G-protein coupled receptor affecting testicular descent; INSL3 receptor; leucine-rich repeat-containing G protein-coupled receptor 8; Leucine-rich repeat-containing G-protein coupled receptor 8; Relaxin family peptide receptor 2; Relaxin receptor 2
基因别名: Gpcr; Gpr106; Great; Lgr8; Rxfp2
UniProt ID: (Mouse) Q91ZZ5
Entrez Gene ID: (Mouse) 140498, (Rat) 363866
oocyte maturation
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
negative regulation of cell proliferation
male gonad development
positive regulation of cAMP biosynthetic process
negative regulation of apoptotic process
