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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:1,000-1:10,000 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human Ras (Q61R Mutant Specific). The exact sequence is proprietary. |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7, with 20% glycerol |
内含物 |
0.025% Proclin 300 |
保存条件 |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2736506 |
Positive Control: Human Ras (Q61R Mutant specific)-transfected 293T whole cell extracts
Predicted Reactivity: Mouse (100%), Rat (100%), Zebrafish (100%), Xenopus laevis (100%), Dog (100%), Pig (100%), Chicken (100%), Bovine (100%), Guinea pig (100%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Ras is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. The process of shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in Ras gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: GTPase NRas; N-ras protein part 4; neuroblastoma RAS viral (v-ras) oncogene homolog; Pan Ras; Transforming protein N-Ras; v-ras neuroblastoma RAS viral oncogene homolog
基因别名: ALPS4; CMNS; HRAS1; N-ras; NCMS; NRAS; NRAS1; NS6
UniProt ID: (Human) P01111
Entrez Gene ID: (Human) 4893
分子生物学功能:
small GTPase
