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产品信息
PEP-283
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
对照试剂 (Ctrl) |
Assay-dependent | - |
| 产品规格 | |
|---|---|
种属反应 |
Rat |
分类 |
Synthetic |
类型 |
Peptide |
偶联物 |
Unconjugated |
形式 |
Lyophilized |
浓度 |
0.5 mg/mL |
纯化类型 |
purified |
内含物 |
no preservative |
保存条件 |
-20° C, Avoid Freeze/Thaw Cycles |
产品详细信息
PEP-283 is a 19 amino acid synthetic peptide whose sequence is derived from rat GLUT4 protein. The sequence of this peptide is (amino to carboxy terminus): E (493)-Q-E-V-K-P-S-T-E-L-E-Y-L-G-P-D-E – N-D (509)
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product, GLUT4, catalog # PA1-1065. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions.
Reconstitute with 0.1 mL of distilled water.
靶标信息
This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Glucose transporter 4 insuline-responsive; Glucose transporter 4, insuline-responsive; glucose transporter glut4; Glucose transporter type 4, insulin-responsive; GLUT-4; insulin responsive glucose transporter; MGC93607; solute carrier family 2 member 4; solute carrier family 2 , member 4; Solute carrier family 2, facilitated glucose transporter member 4
基因别名: Glut4; Slc2a4
UniProt ID: (Rat) P19357
Entrez Gene ID: (Rat) 25139
