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Invitrogen
Repaglinide Recombinant Mouse Monoclonal Antibody (3B12)
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Repaglinide Antibody (MA566336) in SDS-PAGE
SDS-PAGE characterization of Repaglinide under reducing conditions. Lane M: Protein marker (kDa); Lane RLN: Purified Repaglinide Recombinant Monoclonal (Product # MA566336). Repaglinide showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-654.
产品信息
MA566336
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
3B12
抗原
Conjugate of RLN hapten and KLH.
偶联物
形式
Liquid
浓度
5.5 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Repaglinide is a rapid-acting insulin secretagogue used in the management of type 2 diabetes mellitus, primarily targeting postprandial glucose excursions by stimulating early-phase insulin release. Structurally, it is a carbamoylbenzoic acid derivative and belongs to the meglitinide class of drugs. Repaglinide is characterized by its short duration of action, which makes it suitable for controlling blood sugar levels around meal times. It is metabolized primarily in the liver, resulting in limited oral bioavailability due to significant first-pass hepatic metabolism. Efforts to enhance its bioavailability have led to the development of novel delivery systems, such as nanostructured lipid carriers for transdermal application. Repaglinide is often used in combination with other antidiabetic agents like metformin to optimize glycemic control. Synonyms for repaglinide include GlucoNorm, NovoNorm, Prandin, Surepost, and RG.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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