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Intact IgG appears on a non-reducing gel as ~150 kDa band and upon reduction generating a ~25 kDa light chain band and a ~50 kDa heavy chain.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Involved in the reprogramming of X-chromosome inactivation during the acquisition of pluripotency. Required for efficient elongation of TSIX, a non-coding RNA antisense to XIST. Binds DXPas34 enhancer within the TSIX promoter. Involved in ES cell self-renewal. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: hREX-1; Reduced expression protein 1; REX-1; REX1 transcription factor; Zfp-42; Zinc finger protein 42 homolog; Zinc finger protein 754
基因别名: REX-1; REX1; zfp-42; ZFP42; ZNF754
UniProt ID: (Human) Q96MM3
Entrez Gene ID: (Dog) 100856057, (Human) 132625