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Invitrogen
RhoGAP Monoclonal Antibody (D2D6)
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产品信息
MA1-25557
产品规格
宿主/亚型
Mouse
/ IgG
分类
Monoclonal
类型
Antibody
克隆号
D2D6
抗原
Fusion protein corresponding to residues 180-610 of rat RhoGAP.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.7 mg/mL
规格
50 µg
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
产品详细信息
MA1-25557 detects RhoGAP from human, mouse, rat, monkey, and rabbit samples.
MA1-25557 has been successfully used in Immunoprecipitation, and Western blot procedures.
The MA1-25557 immunogen is a fusion protein corresponding to residues 180-610 of rat RhoGAP.
靶标信息
The p190 RhoGAP protein is associated with p120 RasGAP in growth-factor stimulated and tyrosine kinase transformed cells. It functions as a GTPase - activating protein (GAP) for Rho and Rac family proteins, which are involved in regulating cytoskeletal actin and membrane ruffling. The antibody appears to couple signal transduction via Ras and Rho through its association with RasGAP. The presence of two adjacent SH2 domains in the p21 RAS GAP indicates that GAP might interact directly with tyrosine kinases.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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