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Invitrogen
RhoV Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-62781
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.2 mg/mL
规格
20 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: KEVFDSAILS AIEHKARLEK KLNAKGVRTL SRCRWKKFFC FV
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
靶标信息
The Rho subfamily of Ras-related GTPases controls multiple aspects of cell function, including cytoskeletal rearrangement, nuclear signaling and cell growth. Rho V (ras homolog gene family, member V), also known as Rho GTPase-like protein ARHV, CHP or WRCH2 (Wnt-1 responsive Cdc42 homolog 2), is a 236 amino acid protein that controls the actin cytoskeleton through activation of the JNK pathway. A member of the Rho family and small GTPase superfamily, Rho V functions as a lipid anchor at the cytoplasmic side of the cell membrane and is expressed in placenta, pancreas and fetal brain. Rho V is implicated in cell transformation and is encoded by a gene located on human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CDC42-like GTPase 2; GTP-binding protein-like 2; Rho GTPase-like protein ARHV; Rho-related GTP-binding protein RhoV; Wnt-1 responsive Cdc42 homolog 2; WRCH-2
基因别名: ARHV; RHOV; WRCH2
Entrez Gene ID: (Human) 171177
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