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产品信息
A304-572A-T
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Between 418 and 468
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
TBS, pH 7.0 to 8.0
内含物
0.09% sodium azide
保存条件
4° C
运输条件
Wet ice
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine and Orangutan
靶标信息
Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex. Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Chaperone Ric-8A; MGC104517; MGC131931; MGC148073; MGC148074; resistance to inhibitors of cholinesterase 8 homolog A; RIC8 protein; synembryn; Synembryn-A
基因别名: AI114950; RIC-8; RIC8; RIC8A
UniProt ID: (Human) Q9NPQ8, (Mouse) Q3TIR3
Entrez Gene ID: (Human) 60626, (Mouse) 101489
in utero embryonic development
vasculature development
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
gastrulation
regulation of G-protein coupled receptor protein signaling pathway
visual learning
response to light stimulus
cell migration involved in gastrulation
positive regulation of GTPase activity
cell-cell adhesion involved in gastrulation
basement membrane organization
G-protein coupled receptor signaling pathway
