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Recommended positive controls: A431, HeLa, HepG2.
Predicted reactivity: Mouse (96%), Rat (97%), Xenopus laevis (80%), Chicken (88%), Rhesus Monkey (100%), Bovine (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The Formin-like protein 1 (FRL1) gene encodes a formin-related protein which has been implicated in morphogenesis, cyokinesis, and cell polarity. Formins are a conserved class of proteins expressed in all eukaryotes and have one DAD (diaphanous autoregulatory domain), one FH2 (formin homology 2) domain and one GBD/FH3 (Rho GTPase-binding / formin homology 3) domain. FRL1 is located in the cytoplasm and is highly expressed in the spleen, lymph node and bone marrow cells. FRL1 possibly has a role in the control of cell motility, survival of macrophages and cytoskeletal organization.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DRG family-regulatory protein 2; IH1; RWD domain-containing protein 1
基因别名: 0710001K08Rik; 2610002D06Rik; 2700069A07Rik; CGI-24; DFRP2; IH1; PTD013; RWDD1
UniProt ID: (Human) Q9H446, (Mouse) Q9CQK7
Entrez Gene ID: (Human) 51389, (Mouse) 66521