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Invitrogen
S100B Monoclonal Antibody (SH-B1)
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产品信息
MA1-25004
应用
建议稀释比
已发表文章
产品规格
已发表种属
Human,
Pig
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
SH-B1
抗原
Purified, full length, native bovine protein.
偶联物
形式
Liquid
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
产品详细信息
MA1-25004 detects S100 beta from human, rat, bovine, feline, porcine, and rabbit samples.
MA1-25004 has been successfully used in immunohistochemistry (paraffin), ELISA and Western blot procedures. The predicted molecular weight of MA1-25004 is 10.5 kDa.
The MA1-25004 immunogen is purified, full length, native bovine protein.
靶标信息
S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells and are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100B may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
