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产品信息
MA1-21394
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
0.1-0.5 µg/mL | - |
酶联免疫吸附实验 (ELISA) |
Assay-dependent | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Mouse / IgG2b |
分类 |
Monoclonal |
类型 |
Antibody |
克隆号 |
291 |
抗原 |
Highly purified recombinant human SAA (MW: 12 kDa) |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1 mg/mL |
纯化类型 |
Protein G |
保存液 |
PBS, pH 7.2 |
内含物 |
no preservative |
保存条件 |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_557597 |
产品详细信息
MA1-21394 detects SAA in Human samples.
靶标信息
The serum amyloid A family comprises a number of differentially expressed apolipoproteins, acute-phase SAA1 and SAA2, the former being the major component in plasma and constitutive SAAs. Although the liver is the primary site of synthesis of both SAA types extrahepatic production has been reported. The in vivo concentrations increase by as much as 1000 fold during inflammation. Several studies have expressed its importance in the diagnosis and monitoring of various diseases. Pathological SAA values are often detected in association with normal CRP concentrations; SAA rises earlier and more sharply than CRP. Recently, a broader view of SAA expression and function has been emerging.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: amyloid a; Amyloid fibril protein AA; Amyloid protein A; MGC111216; SAA; serum amyloid A protein; Serum amyloid A-1 protein; Serum amyloid A1 protein; Serum amyloid protein A(2-102); Serum amyloid protein A(2-103); Serum amyloid protein A(2-104); Serum amyloid protein A(3-104); Serum amyloid protein A(4-101); Serum Amyloid-A; tumor protein p53 inducible protein 4
基因别名: PIG4; SAA; SAA1; SAA2; TP53I4
UniProt ID: (Human) P0DJI8
Entrez Gene ID: (Human) 6288
分子生物学功能:
apolipoprotein
activation of MAPK activity
receptor-mediated endocytosis
acute-phase response
positive regulation of cytosolic calcium ion concentration
platelet activation
neutrophil chemotaxis
cellular protein metabolic process
innate immune response
positive regulation of cell adhesion
macrophage chemotaxis
lymphocyte chemotaxis
regulation of protein secretion
positive regulation of cytokine secretion
positive regulation of interleukin-1 secretion
negative regulation of inflammatory response
positive chemotaxis
