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Proteintech
SAMHD1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
12586-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Monkey
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SAMHD1 Fusion Protein Ag3287 (1-314 aa encoded by BC036450)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.2 mg/mL
规格
30 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MQRADSEQP SKRPRCDDSP RTPSNTPSAE ADWSPGLELH PDYKTWGPEQ VCSFLRRGGF EEPVLLKNIR ENEITGALLP CLDESRFENL GVSSLGERKK LLSYIQRLVQ IHVDTMKVIN DPIHGHIELH PLLVRIIDTP QFQRLRYIKQ LGGGYYVFPG ASHNRFEHSL GVGYLAGCLV HALGEKQPEL QISERDVLCV QIAGLCHDLG HGPFSHMFDG RFIPLARPEV KWTHEQGSVM MFEHLINSNG IKPVMEQYGL IPEEDICFIK EQIVGPLESP VEDSLWPYKG RPENKSFLYE IVSNKRNGID VDKWD (1-314 aa encoded by BC036450)
靶标信息
This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: dendritic cell-derived IFNG-induced protein; dNTPase; IFN-gamma induced; interferon-gamma-inducible protein Mg11; monocyte protein 5; RP1-132F21.1; SAM domain and HD domain 1; SAM domain and HD domain, 1; SAM domain and HD domain-containing protein 1; unknown intracellular protein; unnamed protein product
基因别名: CHBL2; DCIP; E330031J07Rik; HDDC1; hSAMHD1; Mg11; MOP-5; mSAMHD1; SBBI88
UniProt ID: (Human) Q9Y3Z3, (Mouse) Q60710
Entrez Gene ID: (Human) 25939, (Mouse) 56045, (Rat) 311580
double-strand break repair via homologous recombination
dGTP catabolic process
immune response
cellular response to DNA damage stimulus
deoxyribonucleotide catabolic process
somatic hypermutation of immunoglobulin genes
regulation of innate immune response
dATP catabolic process
protein homotetramerization
defense response to virus
negative regulation of type I interferon-mediated signaling pathway
DNA strand resection involved in replication fork processing
modulation by host of viral RNA genome replication
positive regulation of transcription, DNA-templated
negative regulation of viral life cycle
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
