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Invitrogen
SCAMP4 Polyclonal Antibody
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SCAMP4 Antibody (PA5-112182) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of SCAMP4 in A431 cells. Cells were fixed with 4% PFA, permeabilized with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with SCAMP4 Polyclonal Antibody (Product # PA5-112182) (1:200) at 4°C overnight. Then cells were stained with the Alexa Fluor 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to Cytoplasm.
产品信息
PA5-112182
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived Human SCAMP4 fragment
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
靶标信息
SCAMPs, or secretory carrier membrane proteins, are membrane proteins that are widely distributed and play a role in membrane trafficking. Most SCAMPs, such as SCAMP1, have N-terminal cytoplasmic NPF repeats, 4 central transmembrane regions, and a short C-terminal cytoplasmic tail. These NPF repeats are likely involved in mediating endocytosis. However, other SCAMPs, like SCAMP4, lack the NPF repeats and are thus unlikely to function in endocytosis. SCAMP4 has been associated with diseases such as Neurodevelopmental Disorder With Brain Abnormalities, Poor Growth, And Dysmorphic Facies and Strabismus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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