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Recommended positive controls: IMR32, U87-MG, MCF-7.
Predicted reactivity: Mouse (98%), Rat (97%), Zebrafish (86%), Xenopus laevis (92%), Chicken (93%), Rhesus Monkey (100%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Sec1 family domain-containing protein 1; SLY1 homolog; Sly1p; Syntaxin-binding protein 1-like 2; vesicle transport-related protein
基因别名: C14orf163; FKSG23; KIAA0917; RA410; SCFD1; SLY1; SLY1P; STXBP1L2
UniProt ID: (Human) Q8WVM8
Entrez Gene ID: (Human) 23256