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Immunogen sequence: FTPLYPMLFG GGQERNFRPG TENTPMIAGL GKAAELVTQN CEAYEAHMRD VRDYLEERLE AEFGQKRIHL NSQFPGTQRL PNTCNFSIRG PRLQGHVVLA QCRVLMASVG AACHSDHGDQ PSPVLLSYGV PFDVARNALR LSVGRSTTRA EVDLVVQDLK QAVAQLEDQA
The SCLY gene encodes selenocysteine lyase, an enzyme involved in selenium metabolism, which plays a critical role in the recycling of selenocysteine from selenoproteins. SCLY catalyzes the conversion of selenocysteine into alanine, releasing selenium for reuse in the biosynthesis of new selenoproteins. It is chiefly active in the liver and kidneys, contributing to maintaining selenium homeostasis, which is vital for numerous biological functions due to selenium's role in antioxidant defense and thyroid hormone metabolism. Alterations in SCLY function or expression can affect selenium levels in the body and are associated with disorders related to oxidative stress and metabolic imbalances. Given the importance of selenium in cellular protection and immune function, SCLY is also of interest in studies focusing on dietary supplementation and disease prevention strategies, particularly in conditions like cancer and cardiovascular diseases where oxidative damage is prevalent.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: hSCL; mSCL; Selenocysteine lyase; selenocysteine lyase; Selenocysteine reductase; selenocysteine reductase
基因别名: 9830169H08; A930015N15Rik; hSCL; SCL; SCLY; Scly1; Scly2
UniProt ID: (Human) Q96I15, (Mouse) Q9JLI6, (Rat) Q68FT9
Entrez Gene ID: (Human) 51540, (Mouse) 50880, (Rat) 363285