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Invitrogen
SCN3B Polyclonal Antibody
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产品信息
PA5-28043
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human SCN3B. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.55 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2.
Predicted reactivity: Mouse (99%), Rat (98%), Rhesus Monkey (99%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel beta subunit gene family, and influences the inactivation kinetics of the sodium channel. Two alternatively spliced variants, encoding the same protein, have been identified.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Sodium channel regulatory subunit beta-3; sodium channel, voltage gated, type III beta subunit; sodium channel, voltage-gated, type III, beta subunit; voltage-gated sodium channel beta-3 subunit
基因别名: ATFB16; BRGDA7; HSA243396; KIAA1158; SCN3B; SCNB3
UniProt ID: (Human) Q9NY72
Entrez Gene ID: (Human) 55800
sodium ion transport
nervous system development
positive regulation of heart rate
positive regulation of sodium ion transport
sensory perception of pain
sodium ion transmembrane transport
membrane depolarization
cardiac muscle contraction
regulation of postsynaptic membrane potential
regulation of atrial cardiac muscle cell membrane depolarization
regulation of ventricular cardiac muscle cell membrane depolarization
protein localization to plasma membrane
cardiac muscle cell action potential involved in contraction
ventricular cardiac muscle cell action potential
membrane depolarization during action potential
membrane depolarization during cardiac muscle cell action potential
atrial cardiac muscle cell action potential
SA node cell action potential
regulation of heart rate by cardiac conduction
regulation of sodium ion transmembrane transporter activity
