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Invitrogen
SCRIB Polyclonal Antibody
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SCRIB Antibody (PA5-28628) in IHC (P)
SCRIB Polyclonal Antibody detects SCRIB protein at cytoplasm on human colon carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded colon carcinoma. SCRIB Polyclonal Antibody (Product # PA5-28628) dilution: 1:250. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-28628
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human SCRIB. The exact sequence is proprietary.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.13 mg/mL
规格
13 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol, 1% BSA
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: HepG2, NIH-3T3, JC.
Predicted reactivity: Mouse (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
SCRIB is a cytoplasmic multimodular scaffold protein targeted to epithelial adherens junctions and neuronal presynaptic compartments. SCRIB and its orthologs in vertebrates and invertebrates participate in cell polarization.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: circletail; CRIB1; hScrib; KIAA0147; oSCRIB; PDZ-domain protein scribble; Protein LAP4; Protein scribble homolog; S Vartul; SCRB1; SCRIB1; Scribble; scribble homolog 1; Vartul
基因别名: AI118201; Crc; CRIB; CRIB1; KIAA0147; LAP4; mKIAA0147; SCRB1; SCRIB; SCRIB1; VARTUL
UniProt ID: (Mouse) Q80U72
Entrez Gene ID: (Mouse) 105782
neural tube closure
positive regulation of receptor recycling
auditory receptor cell morphogenesis
multicellular organism development
asymmetric protein localization
cell proliferation
synaptic vesicle targeting
morphogenesis of embryonic epithelium
single organismal cell-cell adhesion
cell migration
cochlear nucleus development
cell differentiation
establishment of apical/basal cell polarity
wound healing
positive regulation of apoptotic process
astrocyte cell migration
negative regulation of mitotic cell cycle
synaptic vesicle endocytosis
positive chemotaxis
auditory receptor cell stereocilium organization
apoptotic process involved in morphogenesis
mammary gland duct morphogenesis
protein localization to adherens junction
activation of GTPase activity
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