Invitrogen

SEC14L1 Polyclonal Antibody

Name: SEC14L1 Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-54415
Availability: InStock

2 篇参考文献

查看其他4个SEC14L1抗体

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (1)

SEC14L1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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SEC14L1 Antibody (PA5-54415) in IHC (P)

Immunohistochemical analysis of SEC14L1 in human testis using SEC14L1 Polyclonal Antibody (Product # PA5-54415) shows moderate cytoplasmic and nuclear positivity in cells in seminiferous duct and strong cytoplasmic positivity in Leydig cells.

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

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Immunogen image

Immunogen Image SEC14L1 Polyclonal Antibody

产品信息

PA5-54415

应用

建议稀释比

已发表文章

免疫组化 (IHC)

查看2篇已发表文章 2篇已发表文章

免疫组化（石蜡） (IHC (P))

1:50-1:200

产品规格

种属反应

Human

已发表种属

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human SEC14L1. Recombinant protein control fragment (Product #RP-102544).

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

50 µg

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2647067

产品详细信息

Immunogen sequence: AMKQYTSNIK KGKEIIEYYL RQLEEEGITF VPRWSPPSIT PSSETSSSSS KKQAASMAVV IPEAALKEGL SGDALSSPSA PEPVVGTPDD

Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 78%.

靶标信息

SEC14L1 may play a role in innate immunity by inhibiting the antiviral RIG-I signaling pathway. In this pathway, functions as a negative regulator of DDX58/RIG-I, the cytoplasmic sensor of viral nucleic acids. Prevents the interaction of DDX58 with MAVS/IPS1, an important step in signal propagation. May also regulate the SLC18A3 and SLC5A7 cholinergic transporters.

仅用于科研。不用于诊断过程。未经明确授权不得转售。