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产品信息
PA5-55955
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human SEC14L1
偶联物
Unconjugated
形式
Liquid
浓度
0.10 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
AB_2647068
产品详细信息
Immunogen sequence: SVFKGAPHEI LIQIVDASSV ITWDFDVCKG DIVFNIYHSK RSPQPPKKDS LGAHSITSPG GNNVQLIDKV WQLGRDYSMV ESPLICKEGE SVQG
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 99%.
靶标信息
SEC14L1 may play a role in innate immunity by inhibiting the antiviral RIG-I signaling pathway. In this pathway, functions as a negative regulator of DDX58/RIG-I, the cytoplasmic sensor of viral nucleic acids. Prevents the interaction of DDX58 with MAVS/IPS1, an important step in signal propagation. May also regulate the SLC18A3 and SLC5A7 cholinergic transporters.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: SEC14-like protein 1
基因别名: PRELID4A; SEC14L; SEC14L1
UniProt ID: (Human) Q92503
Entrez Gene ID: (Human) 6397
