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For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
SEC14L1 may play a role in innate immunity by inhibiting the antiviral RIG-I signaling pathway. In this pathway, functions as a negative regulator of DDX58/RIG-I, the cytoplasmic sensor of viral nucleic acids. Prevents the interaction of DDX58 with MAVS/IPS1, an important step in signal propagation. May also regulate the SLC18A3 and SLC5A7 cholinergic transporters.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: SEC14-like protein 1
基因别名: 1200017E04Rik; 2810012L19Rik; Kiaa4251; Naa-35; PRELID4A; RGD1563123; SEC14L; SEC14L1
UniProt ID: (Human) Q92503, (Mouse) A8Y5H7
Entrez Gene ID: (Human) 6397, (Mouse) 74136, (Rat) 360668