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Invitrogen
SEMA6A Polyclonal Antibody
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SEMA6A Antibody (PA5-143959) in IHC (P)
Immunohistochemistry analysis of SEMA6A in paraffin-embedded section of human rectal cancer tissue. Heat mediated antigen retrieval was performed in EDTA buffer (pH 8.0, epitope retrieval solution). The tissue section was blocked with 10% goat serum. Samples were incubated with SEMA6A Polyclonal antibody (Product # PA5-143959) using a dilution of 1 μg/mL overnight at 4°C. Biotinylated goat anti-rabbit IgG w... View More
产品信息
PA5-143959
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E.coli-derived human Sema6A recombinant protein (Position: H31-N306).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
0.01mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Adding 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
Positive Control - WB: human HEK293 whole cell, human HELA whole cell, human Raji whole cell, human U20S whole cell, human Jurkat whole cell, human CACO-2 whole cell, rat brain tissue, rat PC-12 whole cell, mouse brain tissue, mouse RAW2647 whole cell. IHC: human rectal cancer tissue. Flow: HEPG2 cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
SEMA6A can act as repulsive axon guidance cues. It may play a role in channeling sympathetic axons into the sympathetic chains and controlling the temporal sequence of sympathetic target innervation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Mutant line 997; sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A; Sema Q; Sema VIA; SEMA6A-1; semaphorin 6A-1; Semaphorin Q; Semaphorin VIA; Semaphorin-6A; Semaphorin-6A-1
基因别名: 9330158E07; A730020P05Rik; AI851735; b2b997Clo; HT018; KIAA1368; SEMA; SEMA6A; Sema6A-1; SEMA6A1; SEMAQ; VIA
UniProt ID: (Human) Q9H2E6, (Mouse) O35464
Entrez Gene ID: (Human) 57556, (Rat) 361324, (Mouse) 20358
neural crest cell migration
apoptotic process
cytoskeleton organization
cell surface receptor signaling pathway
nervous system development
axon guidance
organ morphogenesis
negative regulation of axon extension involved in axon guidance
negative chemotaxis
semaphorin-plexin signaling pathway
positive regulation of neuron migration
neuron migration
multicellular organism development
centrosome localization
cell differentiation
