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Immunogen sequence: MDKEYVGFA ALPNQLHRKS VKKGFDFTLM VAGESGLGKS TLINSLFLTN LYEDRQVPEA SARLTQTLAI ERRGVEIEEG GVKVKLTLVD TPGFGDSVDC SDCWLPVVKF IEEQFEQYLR DESGLNRKNI QDSRVHCCLY FISPFGRGLR PLDVAFLRAV HEKVNIIPVI GKADALMPQE TQALKQKIRD QLKEEEIHIY QFPECDSDED EDFKRQDAEM KESIPFAVVG SCEVVRDGGN RPVRGRRYSW GTVEVENPHH CDFLNLRRML VQTHLQDLKE VTHDLLYEGY RARCLQSLAR PGARDRASRS KLSRQSATEI PLPMLPLADT EKLIREKDEE LRRMQEMLEK MQAQMQQSQA QGEQSDAL (1-367 aa encoded by BC012161)
Septin 1 (SEPT1) is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 1-Sep; differentiation 6; differentiation 6 (deoxyguanosine triphosphate triphosphohydrolase); Differentiation protein 6; LARP; MGC20394; Peanut-like protein 3; Protein Diff6; Septin-1; Serologically defined breast cancer antigen NY-BR-24
基因别名: DIFF6; LARP; PNUTL3; SEP1; SEPT1; SEPTIN1
UniProt ID: (Human) Q8WYJ6, (Mouse) P42209, (Rat) Q5EB96
Entrez Gene ID: (Human) 1731, (Mouse) 54204, (Rat) 293507
分子生物学功能: cytoskeletal protein