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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:1,000-1:10,000 | - |
免疫组化（石蜡） (IHC (P)) |
1:100-1:1,000 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human, Mouse |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Recombinant fragment corresponding to a region within amino acids 3 and 185 of Human SERCA3 |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1.5 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7, with 20% glycerol |
内含物 |
0.025% Proclin 300 |
保存条件 |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2545167 |
Recommended positive controls: Jurkat, Raji, K562, BCL-1.
Predicted reactivity: Mouse (99%), Rat (99%), Xenopus laevis (92%), Chicken (88%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
ATP dependent calcium pumps are responsible in part for the maintenance of low cytoplasmic free calcium concentrations. The ATP pumps that reside in intracellular organelles are encoded by a family of structurally related enzymes, termed the sarcoplasmic or endoplasmic reticulum calcium ATPases (SERCA). The SERCA2 gene is subject to tissue dependent processing which is responsible for the generation of SERCA2a muscle-specific isoform expressed in type I (slow) skeletal, cardiac and smooth muscle and the SERCA2b isoform expressed in all cell types. SERCA3 has been found to co-express with SERCA2b in platelets, mast cells, lymphoid cells, and epithelial cells. Due to this pattern of expression it is referred to as the non-muscle form of SERCA.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: adenosine triphosphatase, calcium; ATPase, Ca(2+)-transporting, ubiquitous; ATPase, Ca++ transporting, ubiquitous; Calcium pump 3; calcium-translocating P-type ATPase; sarco/endoplasmic reticulum Ca2+ -ATPase; sarcoendoplasmic reticulum Ca2+ ATPase type 3; Sarcoplasmic/endoplasmic reticulum calcium ATPase 3; SERCA3; SR Ca(2+)-ATPase 3
基因别名: ATP2A3; SERCA3; SERCA3b
UniProt ID: (Human) Q93084, (Mouse) Q64518
Entrez Gene ID: (Human) 489, (Mouse) 53313
分子生物学功能:
primary active transporter
