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Invitrogen
SERPINA3 Polyclonal Antibody
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产品信息
PA5-46907
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Mouse myeloma cell line NS0-derived recombinant human Serpin A3/alpha 1-Antichymotrypsin Asn26-Ala423
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
In direct ELISAs, approximately 20% cross-reactivity with recombinant mouse (rm) Serpin A1 is observed, and less than 3% cross-reactivity with recombinant human (rh) Serpin A1, rhSerpin A3N, rhSerpin A4, rhSerpin A5, rhSerpin A9, rhSerpin C1, rhSerpin F2, and rhSerpin F1/PEDF is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
SERPINA encodes Alpha 1-ACT. It is an early-stage acute-phase plasma protein and a serpin that preferentially inactivates chymotrypsin, cathepsin G, and chymase. Alpha-1-ACT, a serine protease inhibitor, is tightly associated with amyloid plaques in Alzheimer's disease (AD) and in normal aged human and monkey brain. Regulation of the serine proteases and serine protease inhibitors plays an important role in neuromuscular differentiation. Prostate specific antigen (PSA), a chymotrypsin-like serine protease, is predominantly complexed to Alpha-1-ACT.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ACT; Alpha-1-antichymotrypsin; Cell growth-inhibiting gene 24/25 protein; Growth inhibiting protein 24; Growth inhibiting protein 25; growth-inhibiting protein 24; growth-inhibiting protein 25; MGC88254; Serine (or cysteine) proteinase inhibitor clade A member 3; serine (or cysteine) proteinase inhibitor, clade A, member 3; Serpin A3; Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 3; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
基因别名: AACT; ACT; GIG24; GIG25; SERPINA3
UniProt ID: (Human) P01011
Entrez Gene ID: (Human) 12
