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In direct ELISAs, approximately 10% cross-reactivity with recombinant mouse Serpin B8 is observed and less than 2% cross-reactivity with recombinant human (rh) Serpin B6, rhSerpin B9, and rhSerpin A5 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
The superfamily of high molecular weight serine proteinase inhibitors. A critical portion of the molecule, the reactive center loop connects beta sheets A and C. Protease inhibitor-8 (PI8; SERPINB8) is a member of the ov-serpin subfamily, which, relative to the archetypal serpin PI1 (MIM 107400), is characterized by a high degree of homology to chicken ovalbumin, lack of N- and C-terminal extensions, absence of a signal peptide, and a serine rather than an asparagine residue at the penultimate position.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CAP-2; Cytoplasmic antiproteinase 2; Peptidase inhibitor 8; PI-8; protease inhibitor 8 (ovalbumin type); serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 8; Serpin B8; serpin peptidase inhibitor, clade B (ovalbumin), member 8
基因别名: CAP2; PI8; SERPINB8
UniProt ID: (Human) P50452
Entrez Gene ID: (Human) 5271
分子生物学功能: protease inhibitor