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Proteintech
SERPINE2 Recombinant Rabbit Monoclonal Antibody (5O16)
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产品信息
82732-5-RR
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
5O16
抗原
SERPINE2 fusion protein Ag1830
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Immunogen sequence: EELGSNTGIQ VFNQIVKSRP HDNIVISPHG IASVLGMLQL GADGRTKKQL AMVMRYGVNG VGKILKKINK AIVSKKNKDI VTVANAVFVK NASEIEVPFV TRNKDVFQCE VRNVNFEDPA SACDSINAWV KNETRDMIDN LLSPDLIDGV LTRLVLVNAV YFKGLWKSRF QPENTKKRTF VAADGKSYQV PMLAQLSVFR CGSTSAPNDL WYNFIELPYH GESISMLIAL PTESSTPLSA IIPHISTKTI DSWMSIMVPK RVQVILPKFT AVAQTDLKEP LKVLGITDMF DSSKANFAKI TTGSENLHVS HILQKAKIEV SEDGTKASAA TTAILIARSS PPWFIVDRPF LFFIRHNPTG AVLFMGQINK
靶标信息
This gene encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. Thrombin, urokinase, plasmin and trypsin are among the proteases that this family member can inhibit. This gene is a susceptibility gene for chronic obstructive pulmonary disease and for emphysema. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GDN; Glia derived nexin; Glia-derived nexin; Glia-derived nexin/protease nexin I; glial-derived neurite promoting factor; P17; Peptidase inhibitor 7; PI-7; plasminogen activator inhibitor type 1; PN-1; Protease nexin 1; Protease nexin I; protease nexin PN-1; serine (or cysteine) peptidase inhibitor, clade E, member 2; serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; serine (or cysteine) proteinase inhibitor, clade E, member 2; serine protease inhibitor 4; Serine protease-inhibitor 4; Serpin E2; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; serpin peptidase inhibitor, clade E, member 2; SERPINE 2
基因别名: B230326M24Rik; GDN; GDNPF; Gdnpn1; PAI-1; PI-7; PI7; PN-1; PN1; PNI; SERPINE2; Spi4; Spin4
UniProt ID: (Human) P07093, (Rat) P07092, (Mouse) Q07235
Entrez Gene ID: (Human) 5270, (Rat) 29366, (Mouse) 20720
embryo implantation
blood coagulation
negative regulation of cell proliferation
response to radiation
negative regulation of plasminogen activation
negative regulation of sodium ion transport
negative regulation of endopeptidase activity
negative regulation of protein processing
positive regulation of neuron projection development
negative regulation of phosphatidylinositol 3-kinase signaling
cerebellar granular layer morphogenesis
negative regulation of blood coagulation
negative regulation of cell growth
regulation of cell migration
secretion by cell
secretory granule organization
negative regulation of protein catabolic process
mating plug formation
negative regulation of proteolysis
negative regulation of smoothened signaling pathway
regulation of timing of cell differentiation
positive regulation of astrocyte differentiation
detection of mechanical stimulus involved in sensory perception
regulation of synaptic transmission, glutamatergic
long-term synaptic potentiation
innervation
seminal vesicle epithelium development
dense core granule biogenesis
negative regulation of platelet aggregation
response to wounding
negative regulation of peptidase activity
negative regulation of platelet activation
multicellular organism development
nervous system development
cell differentiation
