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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total SESN3.
May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway (PubMed:25263562). May also regulate the insulin-receptor signaling pathway through activation of TORC2. This metabolic regulator may also play a role in protection against oxidative and genotoxic stresses.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Sestrin-3
基因别名: 5630400E15Rik; BC003348; SESN3; SEST3
UniProt ID: (Mouse) Q9CYP7
Entrez Gene ID: (Rat) 315427, (Mouse) 75747